【摘要】 目的探讨体位性睡眠呼吸暂停(positional sleep apnea,PSA)在阻塞性睡眠呼吸暂停综合征(OSAS)患者中发生率及临床特征。方法选自2004年1月～2010年12月在笔者医院睡眠中心经PSG确诊为OSAS的7879例患者中PSA的总体发生率和轻度(5≤AHI<15)、中度(15≤AHI<30)、重度OSAS(AHI≥30)患者中PSA的各自发生率。分别选择AHI相匹配的PSA患者203例(PSA组)和非PSA患者226例(非PSA组)就年龄、BMI、颈围、腰围、PSG各参数及OSAS的可能病程进行了组间比较。结果 OSAS患者中PSA的总体发生率为16.8%(1326/7879)。但PSA的分别发生率在轻度OSAS患者中为34.2%(942/2754),中度OSAS患者中为11.4%(322/2821),在重度OSAS患者中为2.8%(62/2214)。PSA组与非PSA组比较显示PSA患者较非PSA患者BMI低(24.2±2.8 vs 27.1±2.4,P<0.05),颈围细(37.4±1.7cm vs 39.2±1.9cm,P<0.05),腰围无显著组间差异(92.2±4.3cm vs 94.3±3.7cm,P>0.05),仰卧位睡眠占总睡眠时间比例较高(89.4%±6.3%vs 79.8%±7.7%,P<0.05),OSAS的病程可能较短(3.8±2.4 vs 5.6±2.3,P<0.05),但年龄无组间明显差异(47.2±18.4 vs 49.3±19.1,P>0.05)。结论 PSA在程度较轻的SAS患者中发生率较高。与AHI相似的非PSA患者相比,PSA患者的BMI较低、颈围较细,睡眠期仰卧位时间比较长、OSAS的病程可能较短。更多还原

【Abstract】 Objective To investigate the prevalence of positional sleep apnea(PSA) among patients with obstructive sleep apnea syndrom(OSAS) and some clinical characteristics of PSA.Methods The general prevalence of PSA among all OSAS patients and the respective incidences of PSA in mild,moderate and severe OSAS patients were investigated among a total of 7879 OSAS patients undergoing polysomnography(PSG) in sleep centers of author′s hospitals from January 2004 to December 2010.203 PSA patients(PSA group) and 226 AHI-matched non-PSA patients with OSAS(non-PSA group) were selected and compared for their age,body mass index(BMI),neck and waist circumferences,PSG parameters and possible duration of OSAS history between two groups.Results The general prevalence of PSA in OSAS patients was 16.8%(1326/7879).PSA was seen in 942 of 2574 patients(34.2%) with mild OSAS(5≤AHI<15),322 of 2821 patients with moderate OSAS(15≤AHI<30),and 62 of 2214 patients with severe OSAS(AHI≥30).Compared with patients in non-PSA,the patients in PSA group showed the following:a lower BMI(24.2±2.8 vs 27.1±2.4,P<0.05),smaller neck circumference(37.4±1.7cm vs 39.2±1.9cm,P<0.05),higher percentage of sleep in supine posture(89.4%±6.3% vs 79.8%±7.7%,P<0.05),and shorter duration of estimated OSAS history.Conclusion PSA is common particularly in patients with mild OSAS and PSA patients tend to have lower BMI,smaller neck circumference,and possibly a shorter duration of OSAS history than non-PSA patients.更多还原