【摘要】 [目的]了解山东省手足口病的流行特征及流行趋势,为制订手足口病的防治策略提供科学依据。[方法]对2008～2010年山东省手足口病资料进行分析。[结果]2008～2010年山东省手足口病报告病例313 703例(其中重症病例8 482例、死亡53例),年均发病率为111.03/10万。2008～2010年发病率分别为35.20/10万、147.88/10万、149.38/10万。2008～2010年年均发病率,日照市最高为208.76/10万,济宁市最低为59.59/10万;男性为138.31/10万,女性为83.11/10万(P<0.01)。313 703例中,散居儿童占72.65%,幼托儿童占24.41%;0～5岁报告病例的占94.27%;5～7月发病的占61.25%。2008～2010年共报告实验室诊断病例6 423例,其中肠道病毒71型占40.62%,柯萨奇病毒A16型占31.65%,其他肠道病毒占27.73%。全省共报告10例以上的手足口病暴发疫情205起,发病3 345例,其中发生在托幼机构174起,发病2 817例。[结论]2008～2010年山东省手足口病疫情呈高发态势,发病存在明显季节、地区、性别、年龄、病原差异。更多还原

【Abstract】 [Objective]To analyze the epidemiological characteristics of hand,foot and mouth disease(HFMD) in Shandong province,so as to provide basis for the development of effective prevention and control measures.[Methods]The descriptive epidemiological analysis was conducted on the data of HFMD in Shandong province,2008-2010.[Results]A total of 313 703 HFMD cases were reported in Shandong province in 2008-2010,including 8 482 severe cases and 53 deaths.The reported incidence was 111.03/105.The reported incidence was 35.20/105,147.88/105,149.38/105 respectively,2008-2010.The incidence rate of Rizhao was the highest(208.76/105),that of Jining was the lowest(59.59/105);the incidence rate of males and females was 138.31/105and 83.11/105(P<0.01).Of 313 703 HFMD cases,scattered children accounted for 72.65%,kindergarten children accounted for 24.41%;the children under 5 years old accounted for 94.27%;May to July accounted for 61.25%.A total of 6 423 laboratory confirmed cases were reported,of which the cases caused by enterovirus 71(EV71) accounted for 40.62%,those by Coxsackie virus A 16(Cox A16) accounted for 31.65% and those by other enteric viruses accounted for 24.41%.there were 205 outbreaks the cases above 10,with a total of 3 345 cases,174 outbreaks in kindergartens with a total of 2 817 cases.[Conclusion]The incidence rate of HFMD is higher in Shandong province,2008~2010,there are differences in season,district,sex,age,and pathogens.更多还原