【摘要】 目的:对新生儿呼吸衰竭患儿的基本情况、主要病因、临床治疗、预后等情况进行临床回顾性分析,以便总结临床治疗经验。方法:选择2010年1月-2011年12月我院ICU收治的NRF患儿67例进行回顾性分析,资料收集包括患儿的基本情况(胎龄、出生体重、性别、母亲产前疾病、出生时情况等)、疾病诊断、选择性的临床治疗情况、患儿预后等。67例新生儿呼吸衰竭患儿分成三组,胎龄<34周的早产儿,胎龄34～36周的晚期早产儿,胎龄37～42周的足月儿。结果:胎龄<34周的早产儿Apgar评分较其他组偏低(P<0.05)。引起新生儿呼吸衰竭的原发病,胎龄<34周的早产儿新生儿呼吸窘迫综合征占绝大多数(72.0%),晚期早产儿以新生儿呼吸窘迫综合征(41.7%)和肺炎(41.7%)多见,足月儿则以肺炎占半数(50.0%),差异有统计学意义(P<0.05)。新生儿呼吸衰竭治愈56例(83.6%);好转2例(3.0%);放弃治疗9例,病死率13.4%。胎龄<34周患儿住院时间(20.1±6.0)d比晚期早产儿和足月儿长[分别为(12.0±2.2)d及(10.7±2.5)d],有显著差异(P<0.05)。结论:新生儿呼吸衰竭主要由新生儿呼吸窘迫综合征及肺炎所至,应加强对不同时期新生儿呼吸衰竭原发病、多发病的认识。预后受原发疾病、胎龄、并发症诸多因素影响,新生儿呼吸衰竭的治疗持续气道正压通气呼吸支持很重要。更多还原

【Abstract】 Objective:We made a retrospective analysis about the fundamental information,etiological factors,clinical managements and prognosis of the cases of neonatal acute respiratory failure(NRF).The purpose is to summarize clinical experience.Methods:The NRF children select the NICU of our hospital from January 2010 to December 2011 treated 67 cases were retrospectively analyzed.Collection of patient data,which included fundamental characteristics(gestational age,birth weight,gender,antenatal history,history of delivery and resuscitation,eg).The 67 cases of neonatal NRF were divided in 3 groups:gestational age <34 weeks,late preterm(34 to 36weeks),full-term(37 to 42 weeks).Results:The Apgar score of infants less than 34 weeks were less than other groups(P<0.05).The most common cause of NRF were respiratory distress syndrome(RDS) with 72.0%in infants less than 34 weeks,while were RDS with 41.7% and pulmonary infection(PI) with 41.7% in late preterm.For term infants,PI accounted for half of the cause of NRF(P<0.05).56 cases(83.6%) cured and improved 2 cases(3.0%).9 cases quitted,the mortality was 13.4%.Patients less than 34 weeks gestational age need longer hospital stay(20.1±6.0)days than those who were older than 34 weeks gestational age(P<0.05).Conclusion:RDS and PI is the major cause of NRF.We should strengthen the awareness the original incidence of neonatal respiratory failure in different periods.The prognosis involved many factors,including gestational age,complications.Continuous positive airway pressure(CPAP)was one of the most important treatments.更多还原