【摘要】 目的探讨平均红细胞体积(MCV)、红细胞体积分布宽度(RDW)联合血清铁蛋白(SF)检测在缺铁性贫血(IDA)的诊断和鉴别诊断中的临床意义。方法试验分3组,分别是IDA组74例、非IDA组63例以及正常对照组70例,用SysmexXE-5000全自动血液分析仪检测MCV、RDW,罗氏-411全自动化学发光分析仪检测SF,前两组分别与正常对照组比较。结果与正常对照组比较,IDA组MCV值均显著降低(P<0.01),RDW值明显增大(P<0.01),非IDA组中的各类贫血其MCV值正常或增高,其RDW正常或增大。与正常对照组比较,IDA组SF值显著降低(P<0.01);非IDA组增高(P<0.05)。结论联合检测MCV、RDW和SF对鉴别诊断IDA具有重要临床意义,并有显著的社会效应,值得临床推广应用。更多还原

【Abstract】 Objective To investigate the clinical significance of test of mean corpuscular volume(MCV),red cell distribution width(RDW)and serum ferritin(SF)in diagnosis and differential diagnosis of iron deficiency anemia(IDA).Methods All the subjects were divided into 3 groups:group of 74 IDA cases,group of 63 non-IDA cases and normal control group of 70 cases.MCV and RDW of all the subjects were tested by Sysmex XE-5000 automated blood analyzer,and SF was tested by Roche-411 automated chemiluminescent analyzer.Then the data of the first two groups were compared with that of the normal control group.Results In IDA group,the MCV value was significantly lower than that in normal control group(P<0.01),and the RDW value was significantly higher(P<0.01).In non-IDA group,the values of MCV and RDW were either normal or higher than those in the normal control group.The SF value in IDA group was significantly lower than that in the normal control group(P<0.01),and that in the non-IDA group was higher(P<0.05).Conclusions Combined detection of MCV,RDW and SF shows important clinical significance to differential diagnosis of IDA and provides remarkable society benefit.It deserves clinical promotion and application.更多还原