【摘要】 目的评价环喷托酯和托吡卡胺散瞳前后对像差测量的影响。方法选取准分子激光原位角膜磨镶术患者随机分为环喷托酯组15例(30眼)和托吡卡胺组15例(29眼)。两组患者测量像差后,分别给予1%环喷托酯及0.5%托吡卡胺,散瞳后再次测量像差,并比较两组散瞳前后像差球镜值(6mm)和高阶像差的均方根(MRS)值。结果两组暗室瞳孔下像差球镜值均小于综合验光值和散瞳后像差测量值,差异有统计学意义(P<0.05)。两组在暗室下或是散瞳后,随着分析瞳孔的增大,三阶(RMS3)、四阶(RMS4)、五阶(RMS5)、总高阶像差(RMSh)和球差C12逐渐增大,差异有统计学意义(P<0.05),而慧差C7、C8差异无统计学意义(P>0.05)。而在同一分析瞳孔直径下,散瞳前后各阶高阶像差和RMSh、C7、C8差异无统计学意义,散瞳后C12增大,与暗室下C12比较,差异有统计学意义(P<0.05)。在同一瞳孔直径下,环喷托酯组球差值与托吡卡胺组相比,差异无统计学意义(P>0.05)。结论睫状肌麻痹剂影响像差的测量,使球差值增大。更多还原

【Abstract】 Objective To study the effects of cyclopentolate and tropicamide on aberration measurements. Methods The patients were divided randomly into cyclopentolate group (15 cases,30 eyes) and tropicamide group (15 cases,29 eyes) . Wavefront aberrations were measured in dark and measured again with mydriatics. Wavefront sphere (6 mm) and high-order aberrations were compared before and after dilation in both groups. Results The wavefront sphere in dark was more negative than Optometry sphere and wavefront sphere after dilation (P < 0. 05) . In both groups, there were significant differences on high-order aberrations (RMS3,RMS4,RMS5,RMSh) and spherical aberration (P <0.05) ,and no significant differences on the coma (P >0.05) in different analyzing pupil diameter. There were no significant differences on high-order aberrations and coma between scotopic and dilated conditions (P < 0. 05) . And the spherical aberration after dilated increased statistically in both two groups (P < 0. 05) . But there was no significant difference between two groups on spherical aberration in scotopic condition (P > 0. 05) . Conclusions The mydriatics could affect the measurement of aberration,especially the spherical aberration.更多还原