Domino reactions have attracted much high attention in recent years due to its convergence,productivity,facile execution and generation of highly diverse and complex products from easily available starting materials in a single operation.Addition of primary amines to electron-deficient alkynes could generated reactive enaminone(ester) in mild conditions,which have shown versatile reactivity and have been widely used in domino procedure as key reactive intermediate to develop a number of carbon-carbon bond f...