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101例儿童川崎病临床分析

Clinical analysis of 101 Kawasaki disease patients in children

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【作者】 夏珣鹿玲

【Author】 Xia Xun,Lu Ling(Dept of Pediatrics,The First Affiliated Hospital of Anhui Medical University,Hefei 230022)

【机构】 安徽医科大学第一附属医院儿科

【摘要】 目的总结川崎病的临床特点。方法分析我院住院确诊的101例川崎病患儿的临床资料。结果川崎病患儿中男79例,女22例,比例为3.59∶1;5岁以下儿童多见,占89.11%;发病全年散发,以3~4月份最多。口唇潮红皲裂是仅次于发热的重要临床表现;卡斑红的临床发生率相对较高。冠状动脉病变发生率为29.70%,心脏损伤不限于冠状动脉,还见于心肌、心内膜和心包;静脉注射丙种球蛋白(IVIG)联合阿司匹林治疗有效率为91.09%。结论早期诊断,及时应用IVIG对川崎病治疗及预防冠状动脉病变有重要意义。

【Abstract】 Objective To investigate the clinical features of Kawasaki disease(KD).Methods Clinical data of 101 KD patients in children hospitalized from January 2007 to December 2010 were reviewed.Results A total of 101 cases KD children were enrolled in this study with 79 boys and 22 girls.The ratio of male to female was 3.59 ∶ 1.The children under the age of 5 years accounted for 89.11%.KD occurred all the year and more frequently in March and April.In addition to fever,changes in the oral cavity and lips were the most commonly detected clinical signs in our cases;The clinical incidence of the red card spot was relatitvely higher.Coronary artery abnormalities were detected in thirty patients(29.70%).Not just coronary arteritis,KD were detected myocarditis,endocarditis and valvulitis too.The efficiency of intravenous gamma globulin(IVIG) and aspirin therapy in KD was 91.09%.Conclusion It is very important for KD with early diagnosis and timely application of IVIG for and prevention of coronary artery disease.

【关键词】 川崎病冠状动脉疾病
【Key words】 Kawasaki diseasecoronary artery disease
  • 【文献出处】 安徽医科大学学报 ,Acta Universitatis Medicinalis Anhui , 编辑部邮箱 ,2012年03期
  • 【分类号】R725.4
  • 【被引频次】3
  • 【下载频次】117
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