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外源性白蛋白在胃肠外科急危重患者治疗中的应用分析与评价

Application Experience of Exogenous Albumin in Gastrointestinal Surgery Infusion in Critical Patients

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【作者】 范海鹰; 陈德明; 粱健雄; 王国庆;

【Author】 Fan Hai-ying,Chen De-ming,Liang Jian-xiong,et al.(Department of General Surgery,the People’s Hospital of Heshan City,Heshan 529733,China)

【机构】 广东省鹤山市人民医院普通外科;

【摘要】 目的:探讨分析输注外源性人血白蛋白在胃肠外科急危重患者治疗中的临床意义。方法:随机选择2005年1月~2010年1月间在我院行急诊手术并因病情危重而送ICU监护的胃肠外科急危重症患者75例,随机分成研究组40例和对照组35例。两组患者均给予常规治疗和营养支持,研究组患者在常规治疗和营养支持的基础上加用人血白蛋白20g/d,连用1周。对比分析两组患者的死亡率,两组治愈患者的肠鸣音恢复和肛门排气时间以及术后第1天、第7天血清白蛋白、前白蛋白、转铁蛋白等水平。结果:研究组与对照组的死亡率差异无统计学意义(P>0.05);研究组治愈患者术后第7天的血清白蛋白水平高于对照组,差异有统计学意义(P<0.05);研究组治愈患者的肠鸣音恢复、肛门排气时间明显短于对照组,差异有统计学意义(P<0.05);研究组治愈患者术后第7天的血清前白蛋白和转铁蛋白水平与对照组比较差异无统计学意义(P>0.05)。结论:胃肠外科急危重患者输注外源性人血白蛋白可以提高其血清白蛋白水平,改善肠道功能,加快疾病的恢复。

【Abstract】 Objective:Study the infusion exogenous human albumin in gastrointestinal surgery in the treatment of patients with critical clinical significance.Methods:This study randomly chosen 75 patients in our hospital from January 2005 to January 2010.The patients were divided into the research group with 40 patients and the control group with 35 patients.All the patients in both groups were given conventional treatment and nutrition support,the team with the routine treatment and nutrition support in the basis of the employing albumin add 20 g/d,Ed 1 week.A comparative analysis of the two sets of patients mortality,the two groups of cure patients recover and anus bowel sounds sound exhaust time and postoperative day 1,7 days before the serum albumin,albumin,transferrin level,etc.Results:The research group and the control group of mortality difference was statistically significant (P>0.05).The team to cure the postoperative serum albumin levels 7 day higher than those in the control group,the difference was statistically significant (P<0.05).The team to cure patients recover,anus bowel sounds sound exhaust time obviously less than those in the control group,the difference was statistically significant (P<0.05).The team to cure the postoperative serum albumin before the 7 day and transferrin level compared with the difference was not statistically significant(P>0.05).Conclusion:Gastrointestinal surgery critical patients infusion exogenous human albumin can improve the level of serum albumin,improve bowel function,to speed up the recovery of disease.

  • 【文献出处】 中国药物评价 ,Chinese Journal of Drug Evaluation , 编辑部邮箱 ,2012年02期
  • 【分类号】R656
  • 【被引频次】11
  • 【下载频次】102
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