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度洛西汀治疗抑郁症及广泛性焦虑障碍临床应用指导建议

Clinical therapeutic recommendation on duloxtine in treatment of major depressive disorder and generalized anxiety disorder

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【作者】江开达；李凌江；王刚；司天梅；黄继忠；许秀峰；方贻儒；李惠春；陆峥；梅其一；贾福军；李涛；赵靖平；吴文源；张明园；

【Author】 JIANG Kai-da~1,LI Ling-jiang~2,WANG Gang~3,SI Tian-mei~4,HUANG Ji-zhong~1,XU Xiu-feng~5, FANG Yi-ru~1,LI Hui-chun~6,LU Zheng~7,MEI Qi-yi~8,JIA Fu-jun~9,LI Tao~(10),ZHAO Jing-ping~2, WU Wen-yuan~7,ZHANG Ming-yuan~1 (1.Shanghai Mental Health Center,Shanghai Jiaotong University School of Medicine,SHANGHAI 200030, China;2.Institue of Mental Health,the Second Xiangya Hospital of Centre South Univensity,Changsha HUNAN 410011,China;3.Beijing An Ding Hospital,BEIJING 100088,China;4.Institue of Mental Health, Peking University,BEIJING 100083,China;5.First Hospital of Kunming Medical College,Kunming YUNNAN 650032,China;6.The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou ZHEJIANG 310009,China;7.Tongji University School of Medicine,SHANGHAI 200092,China;8. Suzhou Guangji Hospital,Suzhou JIANGSU 215008,China;9.Guangdong General Hospital,Guangdong Pronvincial Institute of Mental Health,Guangzhou GUANGDONG 510120,China;10.Huaxi Hospital of Sichuan University,Chengdu SICHUAN 610041,China)

【机构】上海交通大学医学院附属精神卫生中心；中南大学湘雅二医院精神卫生研究所；北京安定医院；北京大学精神卫生研究所；昆明医学院第一附属医院；浙江大学医学院附属二院；上海同济大学医学院；苏州市广济医院；广东省人民医院广东省精神卫生研究所；四川大学华西医院；

【摘要】抑郁症及广泛性焦虑障碍都是常见的负性情绪障碍,具有患病率高、复发率高、致残率高的特点,目前倡导全病程治疗。新型抗抑郁药均能治疗抑郁症及广泛性焦虑障碍,度洛西汀作为5-羟色胺与去甲肾上腺素再摄取抑制剂类抗抑郁药物的一种,有大量临床证据表明,其在抗抑郁、抗焦虑治疗方面具有起效快、临床治愈率高及安全性好、不良反应少等特点。本文重点介绍近年来国内外在度洛西汀临床应用中的治疗学和循证医学研究进展,结合广大专家的用药经验,为临床医生提供更客观、更规范的治疗选择和治疗方案,以进一步改善患者预后,促进患者回归社会。更多还原

【Abstract】 Depression and generalized anxiety disorder(GAD),which are considered as common negative mood disorder,are charactered by high rate of prevelance,recurrence,and disability,and should be treated over the course of the whole disease.New antidepressants have high efficiency in the treatment of depression and GAD.Duloxetine,which belongs to the SNRIs,is charactered by fast onset of action,higher cure rate and safety and less adverse reaction.The paper mainly introduced the recent research progress in therapeutics and evidence based medicine of duloxetine in clinical practice,and also provided the more objective and standard treatment projects combined with expert experience,in order to improve the prognosis of patient and promote the patient to return to society.更多还原

【关键词】度洛西汀；抑郁症；焦虑症；药物疗法；
【Key words】 duloxtine； depressive disorder； anxiety disorders； drug therapy；

【文献出处】中国新药与临床杂志 ,Chinese Journal of New Drugs and Clinical Remedies , 编辑部邮箱 ,2012年09期

【分类号】R749.72
【被引频次】46
【下载频次】1360

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