【摘要】 目的总结神经梅毒的临床特征及早期诊断依据。方法回顾性分析11例神经梅毒患者的临床分型、临床表现、脑脊液检查及影像学表现。结果所有患者血清快速血浆反应素实验(RPR)和梅素螺旋体明胶凝集实验(TPPA)阳性,其中9例脑脊液检查RPR和TPPA均阳性;2例RPR阴性,TPPA阳性。影像学表现多样化,缺乏特异性。结论神经梅毒的诊断目前无统一的金标准,应结合临床表现、脑脊液检查及影像学检查综合分析,特别是脑脊液的检查尤为重要。更多还原

【Abstract】 Objective To summarize the clinical characteristics and early diagnosis evidence of neurosyphilis.Methods The retrospective analysis was conducted on 11 patients with neurosyphilis treated in the neurologic department of this hospital,including the clinical classification,clinical presentation,laboratory findings of cerebrospinal fluid(CSF)and imaging manifestations.Results Serum RPR and TPPA were positive in all cases.Among them,RPR and TPPA of CSF were positive in 9 cases,only 2 cases had negative RPR and positive TPPA.The imaging findings were diverse without specificity.Conclusion No golden standard has been available for the diagnosis of neurosyphilis,which should be performed the comprehensive analysis by combination with the clinical manifestations,CSF findings and imaging fingdings,especially the CSF detection.更多还原