【摘要】 目的:了解新疆地区维、汉,哈族有消化道症状患者幽门螺杆菌(Hp)感染现状与特征及其在各种消化系疾病中的分布情况;方法:在我院就诊的维、汉、哈族消化道疾病患者共2476例。所有患者均行胃镜检查并用微量胶囊14c尿素酶呼气试验及尿素酶试验测定Hp感染率。对族别、职业、婚姻、生活环境、饮食习惯、经济收入等与Hp感染相关的个人信息采用问卷式流行病学调查。结果:总的Hp感染率为43.58%(1079/2476);男性为40.22%(469/1166),女性为46.56%(610/1310),男女间有统计学差异为P=0.001。维吾尔族Hp感染率59.80%(476/796),哈族50.36%(209/415),汉族31.15%(394/1265),维族与汉族、汉族与哈族、维族与哈族之间均有统计学差异,总χ2=172.462,P<0.001。不同年龄段Hp感染率49岁以下年龄组和49岁以上年龄组之间有统计学差异为P<0.001;20岁以下年龄组的Hp感染率和51岁以上年龄组的Hp感染率之间有统计学差异为P=0.002。21～49岁之间无统计学差异P>0.05;在不同消化系疾病中Hp感染阳性率分别为慢性胃炎56.34%、胃溃疡(GU)89.15%、十二指肠溃疡(DU)88.75%、胃癌50.00%、残胃炎56.86%、功能性消化不良(FV)11.18%、胃食管反流病(GERD)11.20%、食管癌16.36%、其他6.48%。结论:维、汉,哈族总的Hp感染率接近全国普通人群Hp感染率底线。不同消化系疾病中Hp感染率与国内外类似研究报道一致。Hp感染率与区域、环境、民族、年龄、性别,职业、生活方式、饮食习惯及卫生居住条件、婚姻状况等因素密切相关。Hp感染与饮食种类、吸烟、饮酒等因素均无关。更多还原

【Abstract】 Objective: to understand the Xinjiang region Uyghur,Han,Kazak ethnic people current characteristics of Helicobacter pylori infection with a variety of digestive diseases in the distribution; Method: in our hospital perform gastroscopy testing of digestive diseases total 2476 cases for Uyghur,Han,Kazak ethnic people. Endoscopy,micro - capsules 14c urease breath test and urease test determination for Hp infection. On the tribes,profession,marriage,living environment,dietary habits,income,etc. and Hp infection in the relevant personal information with a questionnaire - style epidemiological investigations. Results: The overall Hp infection rate was 43. 58% ( 1079 /2476) ; males 40. 22% ( 469 /1166) ,female 46. 56% ( 610 /1310) , difference between men and women interested in the P = 0. 001. Uyghur Hp infection rate were 59. 80% (476/796) ,Kazak were50.36% (209/415) ,Han were31.15% (394/1265) . Uyghur and Han,Han and Kazak,Uygur and Kazak are statistically significant differences in total,χ2 = 172. 462,P < 0. 001. Hp infection rate in different age groups 49 years age group and 49 years of age or older interested in difference between groups for 0. 001; 20 - year - old age group of Hp infection and 51 years old age group difference of intention between the Hp infection rate P = 0. 002. 21 ～ 49 years of age difference between the non - intended P > 0. 05; In various digestive diseases Hp infection rate of the chronic gastritis is 56. 34% ,the gastric ulcer is 89. 15% ,the duodenal ulcer is 88. 75% ,the gastric cancer is 50. 00% ,the residual gastritis is 56. 60% , the functional dyspepsia is 11. 18% ,the esophageal reflux disease is 11. 20% ,esophagus cancer is 16. 36% and Other diseases is 6. 48% . Conclusions: Uyghur,Han,Kazak Ethnic people overall Hp infection rate of Hp infection rate close to the national bottom line of the general population. Hp infection rate in different digestive diseases that reported in similar studies at domestic and abroad. Hp infection rate with regional,environmental,ethnic,age,sex,profession,lifestyle,eating habits and hygienic living conditions,marital status and other factors closely related. Hp infection and diet type,smoking,drinking and other factors are irrelevant.更多还原