【摘要】 目的探讨对母婴血型不合引起新生儿溶血病进行溶血3项检测试验的重要性。方法对139例新生儿溶血病患儿进行血清学检测,包括直接抗人球蛋白试验、血清游离抗体、红细胞抗体释放试验、ABO以外抗体筛查。结果 139例患儿中被确诊为ABO溶血137例,Rh溶血2例,直接抗人球蛋白试验阳性率84%,血清游离抗体阳性率62.6%,红细胞抗体释放试验阳性率98.6%。血液标本在1~7 d内采集检测阳性率明显较>7d采集高。结论新生儿溶血病3项检测为新生儿溶血病的明确诊断,及早治疗预防提供可靠依据。尽早采集患儿的血液标本进行检验,减少漏检和误检。更多还原

【Abstract】 Objective To explore the importance of serological tests in the hemolytic disease of the newborn due to blood group incompatibility between the mother and fetus.Methods The serological tests,including direct antiglobulin test,serum free antibody test,erythrocyte antibody releasing test and screening of antibody beyond ABO blood group were performed in 139 cases of hemolytic disease of the newborn.Results In 139 cases of hemolytic disease of the newborn,137 cases were diagnosed as ABO incompatibility,and 2 cases Rh incompatibility.The positive rates of direct antiglobulin test,serum free antibody test,and erythrocyte antibody releasing test were 84%,62.6%,and 98.6%,respectively.The positive rate of tests of blood sample collected in 7 days was significantly higher than that after 7 days.Conclusions The serological tests play a key role in the diagnosis,treatment and prevention of hemolytic disease of the newborn.Blood samples should be collected as soon as possible to avoid missed diagnosis and misdiagnosis.更多还原