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98例重型颅脑损伤亚低温治疗效果观察

The study of the clinical effect of mild hypothermia therapy on severe head injury

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【作者】 钟志坚吕加希徐育林尹宏陈庆春

【Author】 ZHONG Zhi-jian,LV jia-xi,XU Yu-lin,et al(Department of Neurosurgery,Guilin Second People’s Hospital,Guilin 541001,Guangxi,China)

【机构】 桂林市第二人民医院神经外科

【摘要】 目的探讨亚低温治疗重型颅脑损伤患者的临床疗效。方法将98例重型颅脑损伤患者(GCS≤8分)随机分为亚低温治疗组和常温组,每组各49例。常温组给予常规治疗,亚低温组在常规治疗的基础上于伤后24小时内给予亚低温治疗,直肠温度控制在32.5~34.5℃,持续2~3天后复温。结果亚低温治疗组病死率、重残率均低于常温组,总有效42例(85.7%),死亡7例(14.2%),与常规治疗组比较,差异有统计学意义(P<0.05)。结论亚低温治疗重型颅脑损伤是一种安全、有效、便于实施的治疗方法,具有改善脑损伤患者的预后,提高患者生存质量的作用,值得临床推广应用。

【Abstract】 Objective To study from the clinical angle the efect of mild hypothermia therapy in treatment of severe head injury.Methods 98 patients with severe head injury patients(GCS≤8 points) were randomly divided into the hypothermia treatment group and the normal temperature group,n=49 cases.Normothermia group received conventional therapy.Hypothermia group on the basis of conventional therapy after injury within 24 hours of mild hypothermia,rectal temperature at 32.5-34.5℃,2-3 days.Results Hypothermia treatment group mortality,severe disability rate lower than the normal temperature group,a good recovery rate of 41(83.6%),mortality rate 7(14.2%),compared with the conventional treatment group,the difference was significant significance P<0.05).Conclusion Hypothermia treatment of severe traumatic brain injury is safe,effective,easy to implement methods of treatment improve the prognosis of patients with brain injury and the quality of life of patients with the role.

【关键词】 颅脑损伤亚低温疗法常规治疗
【Key words】 Head injuryWild hypothermiaTreatment
  • 【文献出处】 西部医学 ,Medical Journal of West China , 编辑部邮箱 ,2012年08期
  • 【分类号】R651.15
  • 【被引频次】5
  • 【下载频次】25
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