【摘要】 目的研究亚临床甲状腺疾病(SCTD)的常规甲状腺超声和彩色多普勒超声血流表现特征。方法纳入亚临床甲状腺功能减退(Shypo)患者41例(甲减组)和亚临床甲状腺功能亢进症(Shyper)患者34例(甲亢组)及甲状腺功能正常者50例(对照组)。所有参加者均完成二维超声和彩色多普勒超声血流检测。检测指标包括甲状腺回声强度,结节外甲状腺及甲状腺下动脉(ITA)测量平均收缩期峰值速度(PSV),血流多普勒超声检测,甲状腺体积和阻力指数(RI)。结果与对照组相比,亚临床甲亢患者的甲状腺下动脉处PSV明显增高(26.3±8.8cm/s,P<0.05),亚临床甲减患者甲状腺内平均PSV值明显增高(20.5±6.7cm/s,P<0.05)。另外,甲状腺自身抗体与甲状腺血流信号强度存在相关性。结论亚临床甲状腺功能障碍患者都存在甲状腺血管密度及血流速度增高;甲状腺彩色多普勒超声检测作为无创性及经济、简便的超声学检测,对亚临床甲状腺功能障碍患者的评价具有较高的价值,可在临床推广应用。更多还原

【Abstract】 Objective To explore ultrasound characteristics of subclinical thyroid disease.Methods 41 cases of subclinical hypothyroidism(Shypo) and 34 cases of subclinical hyperthyroidism(Shyper) were included,and 50 cases of normal thyroid function were set as control group.Subclinical thyroid disease(SCTD) was defined as abnormal serum thyroid stimulating hormone(TSH) level with normal serum free thyroxine(FT4) and free triiodothyronine(FT3) level.All participants were received conventinal ultrasound and color Doppler ultrasound testing.Detection indicators include thyroid sonographic intensity,average systolic peak velocity(PSV) and resistive index(RI) from extra-nodules thyroid parenchyma samplings and inferior thyroid arteries,Color flow Doppler sonography,thyroid volume and resistance index(RI).Results Compared with the control group,average systolic peak velocity at inferior thyroid artery(ITA) in patients with subclinical hyperthyroidism was significantly higher(26.3±8.8 cm/s,P<0.05),whereas higher intra-thyroid average PSV value in patients with subclinical hypothyroidism(20.5±6.7cm/s,P<0.05).In addition,a significant correlation was found between thyroid autoantibodies and thyroid vascular signal intensity.Conclusion Increased vascular density and blood flow velocity were observed in patients with subclinical thyroid diseases.Meanwhile,as a simple non-invasive and economic evaluation measure,Color flow Doppler sonography possesses high promotion value for laboratory evaluation for patients with subclinical thyroid diseases.更多还原