【摘要】 目的探讨肠球菌在泌尿系统感染中的耐药情况,为临床抗感染治疗提供依据。方法对2009年1月～2011年12月门诊和住院患者的1329份尿液标本常规进行病原菌培养与鉴定,药敏试验采用K-B纸片扩散法。结果肠球菌占泌尿系感染的10.2%,以屎肠球菌和粪肠球菌为主,屎肠球菌(35.3%)所占比例高于粪肠球菌(27.2%)。两种肠球菌对万古霉素、替考拉宁、氨苄西林、氯霉素的耐药率均较低,其中粪肠球菌还对青霉素G、呋喃妥因的耐药率较低,分别为21.6%、27.0%。结论肠球菌属对抗生素呈多重耐药,且不同种的肠球菌耐药性差异较大,临床应根据药敏试验结果,合理选择抗菌药物。更多还原

【Abstract】 OBJECTIVE To investigate the drug resistance of enterococci in urinary tract infection,to provide the bases for clinical anti-infective therapy.METHODS The pathogenic bacteria in urine specimens of 1 329 outpatients and inpatients between in January,2009 and in December,2011 were cultured and identified,and antimicrobial susceptibility test that KB disk diffusion method was used.RESULTS Enterococcus in urinary tract infection accounted for 10.2%,of which were main enterococcus faecium and enterococcus faecalis.The proportion of enterococcus faecium(35.3%) was higher than those of enterococcus faecalis(27.2%).Two kinds of enterococcus were with low resistance to vancomycin,teicoplanin,ampicillin,chloramphenicol,one of which enterococcus faecalis was with low resistance to penicillin G(21.6%),nitrofurantoin(27.0%).CONCLUSION Enterococcus is with multiple antibiotic resistance,and drug resistance of different species of enterococci are quite different.The clinical medication should have a rational choice in antimicrobial agents based on susceptibility testing.更多还原