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腺垂体功能减退症及其危象的回顾性分析

Retrospective analysis of anterior pituitary hypofunction and pituitary crises

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【作者】 郑海龙陈小盼宋钦华王转锁

【Author】 ZHENG Hai-long,CHEN Xiao-pang,SONG qin-hua,WANG Chuan-suo. Department of Endocrinology of Affiliated Hospital of Hainan Medical College,Haikou,Hainan 570102,China

【机构】 海南医学院附属医院内分泌科

【摘要】 目的分析腺垂体功能减退症的病因、临床表现及诊治。方法收治61例腺垂体功能减退症患者的临床资料进行回顾性分析。结果席汉氏综合征36例,垂体瘤12例,颅咽管术后放疗6例,空泡蝶鞍4例,自身免疫性垂体炎1例,大部分患者性腺功能缺乏最早,甲状腺激素次之,肾上腺激素缺乏较晚,67%患者3个靶腺功能均有减退。结论腺垂体功能减退症临床表现复杂,提高临床医生对该病诊治水平,避免误诊漏诊。

【Abstract】 OBJECTIVE To analyze the etiology,clinical manifestation,diagnosis and treatment of anterior pituitary hypofunctin.METHODS The clinical data of 61 cases of anterior pituitary hypofunction were collected and analyzed retrospectively.RESULTS The etiology of anterior pituitary hypofunction was as follows:Sheehan’s syndrome(n = 36),pituitary tumor(n = 12),postoperative craniopharyngioma undergoing radiotherapy(n= 6),empty sella syndrome(n = 4),autoimmune hypophysitis(n = 1).Hypogonadism,hypothyroidism and hypoadrenocorticism were found in 67% patients.CONCLUSION Clinical manifestation of anterior pituitary hypofunction is complex.In order to avoid misdiagnosis and missed diagnosis,clinicians should make effort to raise the diagnostic and therapeutic levels of anterior pituitary hypofunction.

  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2012年15期
  • 【分类号】R584.2
  • 【被引频次】11
  • 【下载频次】279
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