【摘要】 [目的]了解深圳市围产儿先心病发生水平及变化趋势,明确流行病学特征,为先心病的病因学研究以及制定预防策略提供科学参考依据。[方法]对深圳市2003～2009年妇幼系统监测资料进行回顾性描述性分析。[结果]深圳市医院监测围产儿先心病发生率呈上升趋势,自2003年的22.14/万上升到2009年43.85/万,围产儿先心病类型以独立先心缺陷为主,动脉导管未闭、室间隔缺损、房间隔缺损分列前3位,高龄产妇、深圳户籍产妇围产儿先心病发生率较高。[结论]深圳市2003～2009年围产儿先心病呈升高趋势,需进一步研究遗传学和环境学影响因素,并扩大监测范围、加强生理性先心缺陷的追踪。更多还原

【Abstract】 [Objective]To learn the prevalence and changing trend of perinatal congenital heart disease(CHD)in Shenzhen,and make clear about the selected epidemiological characteristics and provide some scientific basis for the etiology and preventive strategy of the defects.[Methods]We made retrospective analysis of the data from Shenzhen maternal and children’s healthcare information system between 2003-2009.[Results]The tendency of prevalence of perinatal heart disease was rising significantly based on the hospital surveillance data.The rate of perinatal congenital heart disease was 22.14/10 000 for 2003 and 43.85/10 000 for 2009.The type of CHD was the mainly isolated type.PDA,VSD and ASD ranked the first three types.CHD incidence rate was higher among advanced maternal age group in Shenzhen.[Conclusion]The tendency of prevalence of perinatal CHD in Shenzhen is rising between 2003-2009.Inheritage and Environmental factors need to be studied in future.Surveillance range needs to be enlarged and physiological CHD should be followed.更多还原