【摘要】 目的探讨采用4个月《年龄与发育进程问卷》(中文版)(ages & stages questionnaires-chinese,ASQ-C)预测婴儿12～25月龄时发育结局的能力。方法采用便利抽样方法,抽取3～4月龄发育迟缓高危儿及典型发育儿各32名,婴儿的父母/照看者在家独立完成4个月ASQ-C,12～25月龄时由专业人员用《贝莉婴幼儿发育量表》(第3版)(Bayley-Ⅲ)对2组婴儿进行测试。分别采用Bayley-Ⅲ-2s为发育迟缓的界值及-s为可疑发育迟缓和发育迟缓的界值,检验不同ASQ-C界值的敏感度、特异度及与Bayley-Ⅲ的相关性。结果 Bayley-Ⅲ为x-2s时,ASQ-C界值为x-2s、x-1.5s、x-s的敏感度分别为50.0%、85.7%、85.7%;特异度分别为74.0%、54.0%、30.0%。Bayley-Ⅲ为x-s时,ASQ-C界值为x-2s、x-1.5s、x-s的敏感度分别为44.8%、69.0%、86.2%;特异度分别为80.0%、57.1%、37.1%。两组婴儿的ASQ-3分别与Bayley-Ⅲ各能区之间相关程度低,而且无统计学意义;总样本(n=64)两个量表之间的相关性(r=0.15～0.42)分别较高危儿组和典型发育组高。结论随着4个月ASQ-C界值的提高,预测婴儿可疑发育迟缓及发育迟缓的敏感度可增高85%以上、特异度降低。在使用4个月ASQ-C时,建议采用x-s为界值。更多还原

【Abstract】 Objective To use the 4-month Ages and Stages Questionnaire-Chinese(ASQ-C)to predict developments of 4 months old infants by 15～25 months.Methods 32 4-month-old infants at high risk of developmental disabilities and another 32 infants of the same age at normal development were singled out by convenience sampling method.The 4-month ASQ-Cs were used on the infants at the age of 3 to 4 months by their parents/caregivers at home.Then the Bayley Scales of Infant and Toddler Development-Third Edition(Bayley-Ⅲ)was used at months 12 to 25 by professionals.The cutoff scores of the Bayley-Ⅲwere set at-2s as the standard of developmental delay,-s as the standard of suspected developmental delay and developmental delay,respectively.The sensitivities,specificities and correlations of the ASQ-C with the different cutoff scores were tested.Results When the cutoff score for Bayley-Ⅲwas-2s,the sensitivities of ASQ-C with the scores of-2s,-1.5s and-s were 50.0%,85.7%,and 85.7%,respectively and the specificities were 74.0%,54.0%and 30.0%,respectively.When the cutoff score for Bayley-Ⅲ was-s,the sensitivities of ASQ-C with the scores of-2s,-1.5s and-s were 44.8%,69.0%and 86.2%,respectively,and the specificities were 80.0%,57.1%,37.1%,respectively.Both the risk group and the normal group showed low correlations,with nearly no statistical significance between the 4 month ASQ-C and the Bayley-Ⅲ.But the overall sample had higher predictive correlations(r=0.15～0.42)than each risk or typical one between the two scales,and most of the correlations had statistical significance.Conclusion The increase of 4-month ASQ-C cutoff scores may predict the developmental disabilities by above 85%.It is recommended to set-s as the cutoff score when using the 4-month ASQ-C.更多还原