【摘要】 目的:探讨自发性脑出血患者较长时间应用甘露醇是否会加重血肿周围水肿的严重程度。方法:82例自发性脑出血患者出血量均大于3 mL,并于发病24 h内及发病后4～7 d行头颅CT扫描。将所有病例根据甘露醇应用情况分为甘露醇治疗不满3 d组与甘露醇治疗满3 d组,比较两组血肿周围水肿程度的差异有无统计学意义。结果:甘露醇治疗不满3 d组血肿周围水肿严重程度为(21.7±12.7)mL,与甘露醇治疗满3 d组血肿周围水肿严重程度(27.7±17.8)mL比较,两者差异无统计学意义(P=0.158)。结论:对存在颅高压的自发性脑出血患者连续较长时间(<7 d)应用甘露醇脱水降颅内压,无明显扩大水肿的作用。更多还原

【Abstract】 Objective: To probe whether the secondary brain edema would get heavy on the patients of spontaneous intracerebral hemorrhage(SICH),when the periods of mannitol were longer(more than 3 days and less than 7 days).Methods: Eight-two patients of SICH(volume more than 3 mL) were reviewed with CT scan within 24 h and 4-7 day after SICH onset.Based on the period of mannitol treatment is more than 3 days or not,the patients were divided into two groups compared the volume of secondary brain edema.Results: To compare the volume of secondary brain edema between the group of mannitol treatment period less than 3 days [(21.7±12.7)mL] and the group of mannitol treatment period more than 3 days [(27.7±17.8)mL],there is no statistical differences between two groups of the volume of secondary brain edema.Conclusion: A longer period(less than 7 days) of mannitol treatment wouldn’t enlarge second-ary brain edema on patients with SICH.更多还原