Objective:To assess the effect of hypoxic exposure on Open Field Test behavior in mice.Methods: 6-month-old C57BL/6J male mice were divided into four groups:the control mice(n=8) were housed in room air in normal situations without any treatment;hypoxia 1(8 h/day,n=9),hypoxia 2(12 h/day,n=8),hypoxia 3(24 h/day,n=9) mice were housed in designed hypoxia chamber for 8 weeks.After the hypoxic exposure,all mice were tested for Open Field Test behavior and the weight and heart index were also measured.Results: In...