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萜类化合物对德国小蠊驱避活性的研究

Repellent activity evaluation of terpenoids against German cockroaches

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【作者】 韩招久王宗德姜志宽钱万红陈金珠郑卫青

【Author】 HAN Zhao-jiu1,WANG Zong-de2,JIANG Zhi-kuan1,QIAN Wan-hong1,CHEN Jin-zhu2,ZHENG Wei-qing3(1.Military Medical Institute of Nanjing Command,Nanjing 210002,China; 2.Jiangxi Agricultural University,Nanchang 330045,China; 3.Nanchang Center for Disease Control and Prevention,Nanchang 330045,China)

【机构】 南京军区军事医学研究所江西农业大学南昌市疾病预防控制中心

【摘要】 目的筛选评估萜类化合物对德国小蠊的驱避活性。方法滤纸浸液法生物测定。结果 43个萜类化合物在剂量为340μg/cm2时对德国小蠊雄性成虫驱避活性的初步测试结果显示,羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇等4个化合物表现出了较高的驱避活性。对这4个化合物采用几何浓度梯度进一步测试,并与目前广泛应用的昆虫驱避剂避蚊胺(DEET)进行比较。羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇的驱避中量(RD50)分别为154.7、56.2、165.9和151.3μg/cm2,均低于DEET的RD50(194.5μg/cm2)。结论本项研究结果说明,羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇具有作为蟑螂驱避剂的应用前景。

【Abstract】 Objective To screen and evaluate the repellent activity of terpenoids compounds isolated or synthesized from turpentine against adult male German cockroaches(Blattella germanica).Methods Bioassay with dipped filter papers.Results Among those 43 terpenoids compounds,four compounds,namely hydroxycitronellal,menthol,hydroxycitronellal propionate and campholenic aldehyde propylene glycol 1,3-acetal displayed the most powerful activity in the preliminary screening test using dipped filter paper at the dose of 340 μg/cm2.Further test with geometric series doses for the RD50s(dose of 50% repellency) reveal that the RD50s were 154.7,56.2,165.9 and 151.3 μg/cm2 for hydroxycitronellal,menthol,hydroxycitronellal propionate and campholenic aldehyde propylene glycol 1,3-acetal respectively,less than diethyltoluamide(DEET) with the RD50 of 194.5 μg/cm2.Conclusion It is supposed that these four terpenoids,hydroxycitronellal,menthol,hydroxycitronellal propionate and campholenic aldehyde propylene glycol 1,3-acetal would be potential and promising cockroach repellents.

【关键词】 萜类化合物德国小蠊驱避活性
【Key words】 terpenoidBlattella germanicarepellent activity
【基金】 江苏省自然科学基金项目(编号:BK2009040);国家自然科学基金项目(编号:31060101)
  • 【文献出处】 中华卫生杀虫药械 ,Chinese Journal of Hygienic Insecticides & Equipments , 编辑部邮箱 ,2012年04期
  • 【分类号】S482.38
  • 【被引频次】10
  • 【下载频次】241
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