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非酒精性脂肪性肝病的相关危险因素研究进展

Research on associated risk factors of nonalcoholic fatty liver disease

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【作者】 邹傲史登平

【Author】 ZOU Ao1,SHI Dengping2 Department of Gastroenterology,the Second People’s Hospital of Jingmen,Hubei Province,Jingmen 448000,China

【机构】 湖北省荆门市第二人民医院消化内科

【摘要】 非酒精性脂肪性肝病(NAFLD)是指一群组织病理异常,其发病以胰岛素抵抗为基础,并与肥胖、高脂血症、Ⅱ型糖尿病、原发性高血压等密切相关。疾病早期症状隐匿,如不及时控制可诱发肝硬化及慢性肝病。NAFLD治疗策略有限,因此探讨脂肪肝相关危险因素对降低NAFLD发病及延缓其病程进展具有重要意义。

【Abstract】 Nonalcoholic fatty liver disease(NAFLD) represents a spectrum of histopathologic abnormalities,which with insulin resistance to disease foundation.Those components are closely related with NAFLD which includes obesity,hypertriglyceridemia,low circulating high-density lipoprotein,type 2 diabetes mellitus and essential hypertension.It will lead to cirrhosis of the liver and chronic liver disease if early of disease can not be controlled.Treatment strategies are limited in NAFLD.It is important to discuss associated risk factors of NAFLD into reducing the risk and delay progression.

  • 【文献出处】 胃肠病学和肝病学杂志 ,Chinese Journal of Gastroenterology and Hepatology , 编辑部邮箱 ,2012年01期
  • 【分类号】R575.5
  • 【被引频次】10
  • 【下载频次】176
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