【摘要】 目的:分析不同性别的非冠心病胸痛患者的临床特征。方法:通过冠状动脉造影(CAG)/冠状动脉CT(CTCA)及单光子发射型计算机断层心肌灌注显像(SPECT-MPI)明确诊断为非冠心病胸痛的患者141例,按性别分组,对比分析2组患者的临床特点、误诊原因、病因、用药情况及精神状态。结果:141例中女85例,男56例。女性患者病史长(P<0.01),发病年龄高(P<0.05),吸烟率低,更多伴放射性疼痛及心电图ST-T改变(P<0.01)。81.2%女性和55.4%男性未及时行CAG/CTCA检查而延误诊断。功能性疾病为胸痛主要病因,不同性别差异无统计学意义(P>0.05)。排除冠心病前女性患者用药比例高于男性(P<0.01),排除冠心病后,男性和女性患者焦虑、抑郁均较排除冠心病前明显降低(P<0.01),94.9%女性和全部男性停服药物。结论:非冠心病胸痛患者临床特征存在明显的性别差异,女性更易被长期误诊。更多还原

【Abstract】 Objective:To analyze clinical features of different gender patients with chest pain and non-coronary artery disease.Methods:One hundred and forty-one non-coronary artery disease patients with chest pain were diagnosed by coronary arteriongraphy(CAG)/computerized tomography of coronary artery(CTCA) and single photon emission computed tomography myocardial perfusion imaging(SPECT-MPI).Patients were divided into male and female groups.The clinical features,misdiagnosed cause,etiological factor,medication and mental status were analyzed in two groups.Results:There were 85 females and 56 males in 141 non-coronary heart disease patients with chest pain.There were longer history(P < 0.01),higher age of onset(P < 0.05) and lower smoking rate in female patients.And they were more likely associated with radiation of pain and ST-T changes of electrocardiogram(ECG)(P < 0.01).There were delayed diagnosis in 81.2% female patients and 55.4% male patients without timely perform of CAG/CTCA examination.The functional diseases were the major cause of chest pain,and no significant difference between genders.There was a higher medication proportion before excluding coronary heart disease in female patients than that of male patients(P < 0.01).There were significantly lower patients with anxiety and depression including male and female after excluding coronary heart disease,the negative emotions with female and male patients decreased(P < 0.01).Patients of 94.9% female and 100% male suspend medication.Conclusion:The clinical characteristics of non-coronary heart disease patients with chest pain are significant gender differences.Female patients are more likely long-term misdiagnosis.更多还原