【摘要】 目的:回顾性分析无淋巴结转移的甲状腺微小癌预后的相关因素。方法:收集广东省人民医院2006年1月至2010年12月收治的96例无淋巴结转移的甲状腺微小乳头状癌患者的临床资料,回顾性分析临床、病理及治疗等因素与预后的关系。结果:5年的疾病相关生存率和无复发生存率分别为100%和95.3%。单因素分析显示:癌灶个数、肿瘤大小和甲状腺外侵犯与否与肿瘤复发相关;多因素分析显示,甲状腺外侵犯与否是影响肿瘤复发的独立危险因素,使肿瘤局部复发率增加4倍。结论:甲状腺癌的发生率逐年增加,但伴淋巴结转移病例逐年减少。无淋巴结转移情况下,根治性手术后预防性放射线碘治疗总体预后良好,若术前即出现甲状腺外侵犯,则预后较差。更多还原

【Abstract】 Objective To analyze the prognosis factors of the thyroid micro-carcinoma without lymph node metastasis, retrospectively. Methods Clinical data of 96 patients who were diagnosed as papillary micro-carcinoma without lymph node metastasis were collected. The clinical , pathological, treatment factors and prognosis factors were retrospectively analyzed. Results 5-year disease-related survival and recurrence-free survival rates were 100% and 95.3%. Univariate analysis revealed that : the number of foci, tumor size and extra-capsular extension were related to the recurrence of thyroid cancer ; multivariate analysis revealed that : extra-capsular extension was the independent risk factor of thyroid cancer recurrence ,it will increase the local recurrence rate to 4 times. Conclusions The incidence of thyroid cancer increases every year,but lymph node metastasis is decreasing. For cases without lymph node metastasis, the overall prognosis after radical surgery and prophylactic radiotherapy are good. However, if extra-capsular extension occured preoperatively , the prognosis is poor.更多还原