【摘要】 目的了解临床分离的鲍曼不动杆菌的耐药性,为临床抗感染治疗及合理使用抗菌药物提供依据。方法用常规细菌培养方法从患者标本中分离出细菌,采用MicroScan Walkaway 40微生物分析仪鉴定菌种并进行体外药敏测定。结果 2008～2010年3年中共分离出鲍曼不动杆菌678株,其中2008年106株,2009年207株,2010年365株;16种抗菌药物药敏试验结果,除头孢哌酮/舒巴坦外,其余抗菌药物3年间耐药率均在46.4%～85.9%之间;对16种抗菌药物全耐药的菌株,2008年1株、2009年4株,2010年4株。结论鲍曼不动杆菌耐药率高,应加强药敏监测,合理使用抗菌药物,并建立切实有效的感染控制措施,阻断多药耐药菌传播。更多还原

【Abstract】 Objective To investigate the drug resistance of Acinetobacter baumannii separated and provide basis of clinical anti-infection treatment and rational use of antibiotics for the various departments.Methods The bacteria were isolated from specimens by conventional bacterial culturing,which were identified by the MicroScan Walkaway 40 microbial species analyzer and then performed vitro susceptibility testing.Results 678 Acinetobacter baumannii strains were separated from 2008 to 2010,including 106 strains in 2008,207 strains in 2009,and 365 strains in 2010;the sensitivity testing results indicated that except cefoperazone/sulbactam in 16 antibiotics chose,the drug resistance rate of others was 46.4%-85.9%;there were 1 strain in 2008,4 strains in 2009 and 4 strains in 2010,which showed the drug resistant to all the 16 antibiotics chose.Conclusion The drug resistance of Acinetobacter baumannii was high.The drug sensitivity examination should be strengthened,the antimicrobial drugs should be reasonably used and the effective infection control measures to block the spread of multi-drug resistant bacteria should be established.更多还原