【摘要】 药物诱发的免疫性溶血性贫血(DIIHA)少见。临床表现为中重度溶血性贫血。常见机制是产生药物依赖性抗体,常见药物为抗生素(如头孢替坦、头孢曲松钠和哌拉西林)。少见机制是产生非药物依赖的自身抗体,致特发性温抗体型自身免疫性溶血性贫血,最常见药物是氟达拉滨。治疗首要是停药,并积极处理合并症。更多还原

【Abstract】 Drug-induced immune hemolytic anemia(DIIHA) is seldom seen,whose clinical manifestation is mild-to-severe hemolytic anemia.The common mechanism is the presence of drug-dependent antibodies,and the common drugs are antibiotics,such as cefotetan,ceftriaxone and piperacillin.On other hand,the uncommon mechanism is the presence of non-drugdependent antibodies that can lead to idiopathic autoimmune hemolytic anemia.In such case,the most common drug is fludarabine.Importantly,drug use should be stopped and the complications be actively treated.更多还原