【摘要】 目的 探讨具有间质性肺病及慢性阻塞性肺病(COPD)的肺背景与周围型肺癌(PLC)毛刺征CT表现之间的联系。方法收集经病理证实的100例PLC,将其分为2组,其中间质性肺病及COPD组67例,无间质性肺病及COPD组33例,比较2组病灶CT毛刺征表现的差异。结果 间质性肺病及COPD组毛刺出现率明显较无间质性肺病及COPD组高,间质性肺病及COPD组为88%(59/67),无间质性肺病及COPD组为70%(23/33),具有明显统计学差异(P<0.05)。具有间质性肺病肺背景的PLC的毛刺形态与肺间质疾病的线状影表现一致,周围间质改变越明显,毛刺越多;具有COPD肺背景的PLC毛刺形态多样,为小叶中心肺气肿的壁构成,形态与病灶周围肺气肿严重程度有关。结论 具有间质性肺病及COPD背景的PLC毛刺出现率较高,具有间质性肺病及COPD的肺背景对PLC毛刺征CT表现有影响。更多还原

【Abstract】 Objective To study the relationship between CT manifestations of spicular sign in peripheral lung cancer(PLC) under background complicated by interstitial lung disease and chronic obstructive pulmonary disease(COPD).Methods 100 cases with PLC confirmed by pathological diagnosis were collected and divided into two groups:PLC complicated by interstitial lung disease andf COPD group(group A,67 cases),PLC without the complications of interstitial lung disease and COPD group(group B,33 cases).The differences of CT manifestations of spicular sign between two groups were compared.Results The frequency of spicular sign in group A(88%,59/67) was much higher than that in group B(70%,23/33),there was significant difference between two groups(P<0.05).CT manifestations of spicular sign as linear opacity in PLC complicated by interstitial lung disease were agreement with that in interstitial lung disease.The more alterations were in peripheral intersitium,the more spiculations were in PLC.Spicular appearances of PLC complicated by COPD were multiplicity,which were made up of central lobular emphysema wall and relative to serious degree of emphysema around diseased region.Conclusion The complications of interstitial lung disease and COPD affect on CT manifestations spicular sign in PLC,the frequency of specular sign is significantly increased in PLC complicated by interstitial lung disease and COPD.更多还原