【摘要】 目的 探讨经肝动脉化疗栓塞(TACE)结合立体定向体部伽玛刀治疗肝癌的临床疗效。方法 将原发中晚期肝癌120例随机分为A、B 2组。A组(综合组):60例,采用TACE+体部伽玛刀治疗,先行TACE术1～3次后,再进行体部伽玛刀放射治疗,单次剂量为3～6 Gy;B组(介入组):60例,采用单纯TACE术,且行TACE术均在2次以上。并观察比较肿瘤治疗后的近期疗效、患者生存期及并发症。结果 综合组与介入组1、2年生存率分别为90%、76%和78.6%、40%,2组生存率比较差异有显著性(P<0.05),2组并发症无明显差别。结论 TACE结合体部伽玛刀治疗原发性肝癌是一种安全、有效的方法。更多还原

【Abstract】 Objective To evaluate the therapeutic efficacy of transcatheter arteral chemoembolization(TACE) combined with radiotherapy-body gamma knife in treatment of hepatocellular carcinoma(HCC).Methods 120 patients with HCC were randomly divided into two groups.60 of the 120 patients(A group)were treated with TACE for 1-3 times after given radiotherapy-body gamma knife 2-3 weeks.60 of the 120 patients(B group) were simply treated with beyond two times TACE.The short-term therapeutic effect,survival rate and complications of the patients were assessed.Results The survival rate was 90% in 1 year and 76 % in 2 yeaars in group B,78.6 % and 40% in group A,respectively.The difference between group A and B was statistical significance(P<0.05).There was no significant difference of complications in two group s.Conclusion TACE combined with radiotherapy-body gamma knife is a safe and effective method for treating hepatocellular carcinoma.更多还原