【摘要】 目的 探讨胸腺瘤的CT征象与Masaoka临床-病理分期以及预后影响因素的相关性。方法 回顾性分析45例经手术病理证实为胸腺瘤患者术前的CT资料和一般临床资料,比较侵袭性与非侵袭性胸腺瘤的CT表现,并对7例复发患者的CT征象进行相关性分析。结果45例中,非侵袭性胸腺瘤11例,侵袭性胸腺瘤34例,CT上二者在形态不规则、边缘毛糙/不清、肿瘤内有囊变/坏死或钙化、纵隔脂肪层浑浊/消失、大血管浸润、心包受侵以及不均匀强化中有显著差异(P<0.05)。7例患者术后出现复发或转移,与边缘毛糙/不清、淋巴结肿大、胸膜受侵、大血管浸润及其他脏器受侵有显著相关性(P<0.05)。结论 CT有助于术前鉴别侵袭性与非侵袭性胸腺瘤,为设计合理治疗方案以及术后判断预后提供有价值的信息。更多还原

【Abstract】 Objective To investigate the computed tomography(CT) imaging findings of thymoma and the relativity between CT features,Masaoka staging system and prognosis.Methods 45 patients with thymomas confirmed by surgery and pathology were retrospectively reviewed.CT findings of invasive and noninvasive thymoma were comparatively analysed.CT features in 7 cases with recurrent thymomas were also analysed.Results Of 45 cases with thymomas,1 1 cases were noninvasive thymomas and 34 cases were invasive thymomas.There were significant differences between invasive and noninvasive thymomas in CT findings,including irregular contours,rough margins or no clear boundary,necrotic or cystic component of the tumors,calcifications within the tumors,mediastinal fat infiltration,pericardial effusion,great vessel infiltration and heterogeneous enhancement(P<0.05).7 cases underwent tumor recurrence and metastasis,which were correlated with rough margin or no clear boundary of the tumors,lymphnode enlargement,pleural invasion,breat vessel infiltration and other tissue invasion(P<0.05).Conclusion CT is useful in differentiating invasive from noninvasive thymoams and plays an important role in management for reasonable therapy and evaluation of prognosis clinically.更多还原