【摘要】 目的:探讨B细胞慢性淋巴细胞白血病(chronic lymphocytic leukemia,CLL)的免疫表型特点。方法:应用流式细胞仪分析24例初诊B-CLL患者外周血或骨髓的免疫表型。结果:24例初诊CLL患者21例CD5+、CD23+最终被确诊为CLL,其余3例分别被诊断为套细胞淋巴瘤(MCL)和滤泡淋巴瘤(FL)。结论:免疫分型对CLL的诊断及鉴别诊断有重要意义,CD38和ZAP70的表达是CLL患者预后的重要指标。更多还原

【Abstract】 Objective:To investigate the immunophenotypic characteristics of B-cell chronic lymphocytic leukemia(B-CLL).Methods: Flow cytometry was used to analyze the phenotype of peripheral blood or bone marrow from 24 cases who were newly diagnosed as B-CLL.Results:Twenty one out of 24 cases of CLL patients was diagnosed of CLL finally because of CD5+,CD23+,the rest cases were diagnosed as mantle cell lymphoma(MCL) and follicular lymphoma(FL).Conclusion: Immunophenotyping was very useful for the diagnosis and differential diagnosis of CLL,and the expression of CD38 and ZAP70 were important prognostic indicators of CLL patients.更多还原