【摘要】 通过羟基磷灰石/聚乳酸(HA/PLLA)纳米复合材料在模拟体液(SBF)中的浸泡实验评价该材料的生物学性能。测试发现HA/PLLA纳米复合材料在浸泡过程中SBF的pH值呈现下降趋势,HA的存在缓冲了PLLA的酸性;复合材料表面有类骨磷灰石层沉积,并有"蚕茧状"类骨磷灰石颗粒和夹有短棒状晶体的片状晶体簇生成;同时复合材料的降解导致表面形成大量蜂巢状多孔。因此原位法制备的HA/PLLA纳米复合材料具有较好的生物活性和可降解性。更多还原

【Abstract】 The aim of this research was to estimate the bioactivity of nano-hydroxyapatite /poly(L-lactic acid) composites in simulated body fluid.In vitro test showed that the pH value of simulated body fluid(SBF) declined gradually and the existence of hydroxyapatite(HA) particles neutralized the acid degradation product of poly(L-lactic acid)(PLLA).Bone-like apatite deposited on the surface,and silkworm-like crystals and plate-like clusters appeared after soaking.At the same time,there were many honeycomb-like pores caused by nano-composite degraded.The results indicated that the hydroxyapatite /poly(L-lactic acid) nano-composites have good bioactivity and degradation characteristics.更多还原