【摘要】 子痫前期是导致全球孕产妇和围生儿发病和死亡的主要原因之一。子痫前期的病因至今尚未明确,但是大量研究已证实多系统的氧化应激与子痫前期发病机制有关。辅酶Q10是目前受到广泛关注的一种抗氧化剂,并且已有辅酶Q10药品制剂问世。本文从细胞水平简要总结了氧化应激与子痫前期发病机制的关系,并讨论了辅酶Q10对子痫前期中氧化应激的防治作用。希望为子痫前期的早期治疗及改善预后提供新的思路。更多还原

【Abstract】 Preeclampsia is a major cause of maternal and fetal morbidity in the world.Although the etiology of preeclampsia is still unclear,a large number of researches have confirmed that multi-system oxidative stress(OS) is related to the pathogenesis of preeclampsia.Coenzyme Q10 is an antioxidant that is widely concerned now,and has been made into pharmaceutical products.This arti-cle has made a brief summary about relationships between OS and preeclampsia in cellular level,and has discussed the action of CoQ10 on OS in preeclampsia.We hoped for providing the new ideas to the early treatment and and the improvement of the prognosis in preeclampsia.更多还原