【摘要】 目的检测正常中晚期孕妇的凝血四项及D-二聚体指标,了解正常中晚期孕妇的凝血与纤溶功能状态及临床意义。方法凝血四项测定均为凝固法,D-二聚体为免疫比浊法。在Sysmex CA7000全自动血凝仪上进行检测。结果正常妊娠中晚期孕妇与正常非孕妇女对照组比较,PT、APTT时间明显缩短(P<0.05);FIB显著增高(P<0.01);TT差异不明显(P>0.05);D-二聚体水平差异有统计学意义(P<0.05)。结论妊娠中晚期由于凝血功能增强,抗凝及纤溶功能减弱,出现妊娠期高凝状态,有利于产后快速有效止血。产前凝血功能的检测,对预防产科并发症(如DIC及羊水栓塞等)有重要的临床意义。更多还原

【Abstract】 Objective To detect the result of four items blood coagulation and plasma D-dimer in healthy women in mid-late women,so as to understand their coagulation and fibrinolysis.Methods Four items blood coagulation were assayed with coagulation method,and D-dimer with immune-turbidity method.Both were tested on sysmex Ca-7000 full-Automatic coagulation analyzer.Results Compared with the healthy non-pregnant women,women in mid-late pregnancy had shorter PT and APTT(P<0.05),and higher FIB(P<0.01).There was no evident difference on TT(P>0.05).The significant difference was also found in D-dimer level between the two groups(P<0.05).Conclusions Due to enhanced coagulation and decreased fibrinolytic activity,hypercoagulability usually occurs in mid-late pregnancy,which is useful to stop post-partum bleeding rapidly and effectively.Therefore,it is clinically important to examine the coagulation function prenatally,especially to avoid obstetric complications such as DIC and amniotic fluid embolism.更多还原