【摘要】 目的:通过玉米低营养饲料建立动物模型系统,提出损益指数(BDI)的概念,并进行累积积分(GS),建立食品功效安全的BDI-GS新评价体系。方法:本体系以处于生长期正常ICR小鼠为研究对象,综合评价食物的营养、保健功效及安全性。以单纯普通玉米饲料喂食小鼠作空白对照组,大豆制成玉米掺和饲料为阳性受试物实验组,通过动物整体实验,取小鼠体质量、9项脏器组织质量、系数及其BDI和GS等指标,并进行血清生化指标分析测试,考察BDI-GS评价体系在食物营养、保健功效及安全性综合评价方面的合理性、科学性和可行性。结果:体质量变化趋势及体质量、脏器质量BDI大小,可初步判定大豆有一定的营养功效;脏器系数BDI和BDI累积积分说明大豆有保健功效,尤其是胸腺系数BDI,随着剂量的增加有增加趋势,且有显著性统计学差异(P<0.01)。结论:通过本研究建立一种直观、全面、简单、经济的综合评价不同类别食物及饮品功效安全的新评价体系和方法。更多还原

【Abstract】 Objective: In the present study,a novel BDI-GS evaluation system for the functions and safety of foods was established through accumulated general scores(GS) as well as benefit-damage index(BDI) from an animal model by feeding lownutrient corn.Methods: Mice at the normal growth stage were used as test subjects to evaluate the comprehensive nutrition and health-promoting functions as well as safety of foods.Control mice were fed simply on common maize,and trial mice were fed on maize supplemented with soybean.Body weight,9 viscera weights and indices,BDI,GS and serum biochemical parameters in mice were determined to analyze the rationality,scientificity and feasibility of BDI-GS evaluation system in nutrition and health-promoting functions as well as safety of foods.Results: Changes in body weight,viscera weight and BDI in mice could reflect the nutritional benefits of soybean.BDI and BDI accumulation index indicated health-promoting functions,especially thymus index BDI revealed an increase in a dose-independent manner and a significant difference(P < 0.01).Conclusion: An intuitive,overall,easy,economical comprehensive evaluation system for the functions and safety of various foods and drinks has been established.更多还原