【摘要】 阿尔茨海默病(Alzheimer’s disease,AD)是与年龄相关的神经退行性疾病。记忆障碍通常是AD最早期和最明显的特征。β-淀粉样蛋白(amyloid-β,Aβ)沉淀(老年斑)、Tau蛋白引起的神经纤维缠结是AD的典型病理特征。许多研究证实两者之间存在着极为复杂的互为因果关系,共同造成神经元的损害。更多还原

【Abstract】 Alzheimer’s disease(AD) is an age-related neurodegenerative disease with memory disorder which is usually the earliest and most obvious feature.β-amyloid protein(amyloid-β,Aβ) deposition(senile plaques) and neurofibrillary tangles composed of Tau protein are the two typical pathological features in AD.Many researches confirmed that the two proteins interact on each other and cause neuronal damage.更多还原