【摘要】 目的:观察健脾消积汤治疗癌因性疲乏对患者生活质量的影响。方法:将62例患者随机分为治疗组32例与对照组30例,2组同型肿瘤患者采用相同的化疗方案治疗;21天为1个周期,2个周期评价疗效。治疗组加用健脾消积汤治疗;21天为1个疗程,2个疗程评价疗效。观察2组治疗前后生活质量量表EORTC-QLQ-SF-36调查问卷评价、疲乏状况变化及不良反应。结果:2组生活质量量表EORTC-QLQ-SF-36问卷评分比较,治疗组躯体功能、角色功能、情绪功能、物理症状及整体状况均优于对照组,差异有统计学意义(P<0.05);而认知功能、社会功能差异无统计学意义(P>0.05)。2组疲乏状况比较,治疗组疲乏状况有明显减轻,对照组无变化;治疗组优于对照组(P<0.05)。不良反应比较,治疗组低于对照组(P<0.05)。结论:健脾消积汤具有提高机体免疫功能,改善患者临床症状及疲乏状况,提高生活质量,延长生存期。更多还原

【Abstract】 Objective:To observe effect of Jianpi Xiaoji Decoction on life quality of patients with cancer-related fatigue.Methods:Sixty-two patients were randomized to treatment group(n = 32) and control group(n = 30),both groups received radiotherapy for 2 treatment periods,21 days per period.The control group took Jianpi Xiaoji Decoction for the same treatment period.After treatment,EORTC-QLQ-SF-36 was used to evaluate fatigue conditions and adverse event was collected.Results:According to EORTC-QLQ-SF-3,the treatment group was better than control group in terms of physical function,role identification,emotions,signs and symptoms and overall conditions(P < 0.05).Two group was not statistically different in terms of cognitive functions and social function(P > 0.05).And treatment presented less adverse event(P < 0.05).Conclusion:Jianpi Xiaoji Decoction can improve immunity functions,relieve clinical symptoms and fatigue condition,improve life quality and extend survival time.更多还原