【摘要】 丙酮酸乙酯(ethyl pyruvate,EP)是一种稳定的丙酮酸酯类衍生物,它对于发生急性损伤的器官(如心脏、脑和肾脏)具有显著的保护作用。然而其治疗作用和机制尚未阐明,本文就EP的药理抗炎作用和可能的机制进行综述。更多还原

【Abstract】 Ethyl pyruvate(EP),a stable lipophilic ester derivative of pyruvate,is remarkably effective in protecting organs(brain,heart and kidney) against acute injury.However,the therapeutic potential and possible mechanisms remain to be elucidated.In this review,the anti-inflammatory effects and potential mechanisms of EP are discussed.更多还原