【摘要】 目的 运用导管术构建新西兰兔充血性心衰的心气虚模型。方法 运用导管术造成兔的超容量负荷型心衰模型，造模后15 d和30 d从动物的一般状态、饲料消耗指数、体重增加指数、心率、呼吸频率和心电图等指标进行量化观察。结果 与正常对照组比较，SBP、DBP和LVSP等血流动力学指标显著性下降，造模后15 d、30 d家兔活动明显减少、精神萎靡、抓起反抗力度减轻，饲料消耗指数与体重增加指数降低，呼吸频率和心率明显增加，且心电图出现异常Q波、ST段抬高。结论 以动物的一般状态、心率、呼吸频率、心电图表现、饲料消耗指数和体重增加指数等指标基本可以定性定量地反映出充血性心衰的心气虚模型特征。更多还原

【Abstract】 Objective To construct congestive heart failure rabbit model of heart Qi deficiency caused by catheterization. Methods Construct cardiac hyper-volume overload, rabbit heart failure model was caused by catheterization.Fifteen and 30 days after modeling, the general status, feed consumption index, body weight index, heart rate, respiration and ECG were observed and measured. Results Compared with the normal control group, SBP, DBP, LVSP and other hemodynamic index decreased significantly.After 15 and 30 days of modeling, the activity of model’s rabbit was significantly reduced, the apathetic,efforts of resisting grab were reduced, feed consumption and body weight indices were decreased,breathing and heart rate were increased significantly, abnormal Q wave was appeared, and ST wave segment was elevated. Conclusion The heart rate, respiration, ECG, body weight and feed consumption index and other indicators can qualitatively and quantitatively reflect the heart failure model of heart qi deficiency.更多还原