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济南市体检人群脂肪肝检出率及危险因素

Detectable rate and risk factors of fatty liver in the Jinan physical examination population

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【作者】 高西美王静杨晓云高立菊王凯

【Author】 GAO Xi-mei1,WANG Jing2,YANG Xiao-yun1,GAO Li-ju3,WANG Kai4(1.Health Examination Center;2.Intensive Care Unit;3.Department of Bone Surgery;4.Department of Hepatology, Qilu Hospital of Shandong University,Jinan 250012,China)

【机构】 山东大学齐鲁医院健康体检中心山东大学齐鲁医院重症医学科山东大学齐鲁医院骨外科山东大学齐鲁医院肝病科

【摘要】 目的了解济南市体检人群脂肪肝患病情况,探讨其主要危险因素,为脂肪肝一级预防提供依据。方法2011年3月对济南市2 162名18岁以上体检人员进行调查,分析其年龄、身高、体质量、行为习惯及肝功、血脂、空腹血糖等血清学指标,同时行肝脏超声检查。结果济南市体检人员脂肪肝检出率为20.3%,男性检出率高于女性(P<0.05),男性40~岁组检出率最高,女性50~岁组检出率最高。Logistic回归分析显示,性别、体质量指数、腰围、血压、空腹血糖水平、甘油三酯、高密度脂蛋白胆固醇、饮酒等与脂肪肝密切相关。结论济南市成人脂肪肝检出率较高,且以中老年多见。男性、肥胖、高血压、高脂血症、高血糖、饮酒等是脂肪肝患病的危险因素。

【Abstract】 Objective To investigate the detectable rate of fatty liver and its associated risk factors in adult residents who had a physical examination in Jinan.Methods 2 162 adult residents aged over 18 years old who had a physical examination were included in the study.Age,height,weight,behavioral habits,liver function,serum lipid profile,fasting blood sugar and ultrasonographic features of the liver were collected.Results The overall detectable rate of fatty liver in Jinan city adult residents was 20.3%(22.0% in males vs 18.0% in females,P<0.05).It reached the peak value in the male group of 40-years old and in the female group of 50-years old.Logistic regression analysis showed that sex,body mass index(BMI),waist circumference,blood pressure,fasting blood sugar,triglyceride,high-density lipoprotein cholesterol and drinking were the risk factors which significantly correlated with fatty liver.Conclusions The detectable rate of fatty liver is high among adult residents in Jinan.Male,obesity,hypertension,hyperlipidemia,hyperglycemia and drinking are closely associated with fatty liver.

【基金】 山东省科技厅软科学项目(2010RKGA2027);山东省科学技术发展计划项目(软科学部分,B200330)
  • 【文献出处】 山东大学学报(医学版) ,Journal of Shandong University(Health Sciences) , 编辑部邮箱 ,2012年06期
  • 【分类号】R575.5
  • 【被引频次】7
  • 【下载频次】118
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