【摘要】 从了哥王根茎石油醚提取部位分离得到3个木脂素,采用核磁共振(1H-NMR、13C-NMR、DEPT)和ESI-MS波谱解析技术对其结构进行鉴定,最终分别确定为(-)-pinoresinol(1)、arctigenin(2)、bursehernin(3),且化合物3为首次从了哥王中分离得到;并采用MTT法和SRB法检测上述化合物的抗肿瘤活性,发现化合物1、2具有微弱的细胞抑制作用。更多还原

【Abstract】 Three kinds of known lignans were isolated from the petroleum extracts of the roots and stems of Wikstroemia indica(L.)C.A.May using classic phytochemistry technique in the present work.They were identified as(-)-pinoresinol(1),arctigenin(2) and bursehernin(3) by spectroscopic analysis methods including 1H-NMR,13C-NMR,DEPT and ESI-MS.Compound 3 were isolated for the first time.The bioactivity against tumor was evaluated using the methods of MTT and SRB,and compounds 1,2 showed a weak effect on tumor inhibition.更多还原