The effects on Vibrio in sediment on the same density of Apostichopus japonicus for probiotics were studied on 2010 and 2011 in this paper.The results showed that the new circle was the total number of vibrios in sediment was significantly lower than the old circle,And after the probiotics,the test group of circle the total number of vibrios in sediment was significantly lower than the control group.Inhibition period of 12 days when the concentration at 1.25×106 cfu/L.The results showed that probiotics coul...