【摘要】 目的:观察缺血性脑卒中患者颈动脉粥样硬化斑块和血脂变化及其相互关系。方法:对80例经头颅CT和(或)MRI检查确诊的缺血性脑卒中(脑卒中组)和75例健康体检者(对照组),采用多普勒超声检测颈动脉内膜-中层厚度(IMT),并同时检测血脂水平。结果:脑卒中组颈总动脉、颈内动脉及颈总动脉分叉部IMT均明显高于对照(p<O.01);脑卒中组颈动脉粥样斑块检出率显著高于对照组(p<0.01);脑卒中组血清总胆固醇(TC)、低密度脂蛋白(LDL)水平明显高于对照组(p<0.05);脑卒中组有斑块亚组明显高于无斑块亚组(p<0.05)。结论:颈动脉IMT、斑块的部位和性质及血脂变化与缺血性脑卒中的发生密切相关。更多还原

【Abstract】 Objective To study the relationship of carotid-artery atherosclerotic plaque and lipids changes to ischemic stroke.Method Carotid-artery intima-medial thickness (IMT),location,amount and property of the carotid atherosclerotic plaque of the common carotid and internal carotid were examined with color doppler ultrasound and lipid levels in 80 patients with ischemic stroke (stroke group) confirmed by cranial CT and(or)MRI and 75 cases of healthy subjects as controls (control group).Results IMT of common carotid,internal carotid and bifurcation of common carotid in ischemic stroke patients were obviously higher than that in control group(p<0.01).The prevalence of carotid atherosclerotic plaque in stroke group was obviously higher than that in control group(p<0.01); Total cholesterol (TC),low-density lipoprotein (LDL) levels in stroke group was obviously higher than that in control group (p<0.05);stroke group plaque sub-group was obviously higher than that non-plaque sub-group (p<0.05). Conclusions The development of ischemic stroke is closely correlatedwith the carotid-artery IMT,location and property of the carotid plaque and serum lipids.更多还原