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心理干预对干扰素致丙肝患者抑郁症康复及生活质量的影响
Psychological intervention of interferon-induced depression rehabilitation and quality of life in hepatitis C patients
【摘要】 目的探讨心理干预对干扰素所致慢性丙型病毒性肝炎患者抑郁症康复及生活质量的影响。方法将100例使用干扰素抗病毒治疗的慢性丙肝患者,随机分成实验组50例和对照组50例,对照组采用常规治疗和护理,实验组在此基础上增加心理干预。应用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)量表,比较两组患者评分差异来评价两组患者焦虑及抑郁情况。同时采用中文版普适性健康调查量表对患者进行生活质量测定,比较两组患者生活质量的变化。结果干预前两组HAMD、HAMA评分差异与对照组比较无统计学意义(P>0.05),治疗1个月,2个月后,两组HAMD、HAMA评分均比干预前显著下降(P<0.05),实验组下降更明显。实验组中文版普适性健康调查量表生活质量8项因子评分均明显高于对照组,生活质量有较大的变化。结论心理干预对干扰素所致慢性丙肝患者抑郁症有改善其焦虑、抑郁情绪的作用,促进疾病的康复,明显提高患者的生活质量。
【Abstract】 Objective To investigate the psychological intervention interferon due to chronic hepatitis C patients with depression rehabilitation and quality of life. Methods 100 cases of patients with chronic hepatitis C antiviral therapy using interferon,experimental group of 50 patients and a control group of 50 patients were randomly divided into control group with conventional treatment and care,the experimental group to increase psychological intervention on this basis.Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA) scale to evaluate the two groups of patients with anxiety and depression,the two groups were compared differences in scores.Determination of the quality of life of patients while using the Chinese version of the universal health survey scale,the two groups were compared quality of life changes. Results 2 groups before intervention HAMD,HAMA score differences with the control group was not statistically significant(P>0.05),treated a month,two months later,the group HAMD,HAMA score than before the intervention significantly decreased(P<0.05),the experimental group decreased more significantly,universal health survey of the Chinese version of the experimental group 8 Scale quality of life factor scores were significantly higher than the larger changes in the quality of life. Conclusions Psychological intervention to improve the role of anxiety,depression,depression in patients with chronic hepatitis C due to interferon,promote the rehabilitation of the disease,and significantly improve the quality of life of patients.
- 【文献出处】 齐齐哈尔医学院学报 ,Journal of Qiqihar University of Medicine , 编辑部邮箱 ,2012年23期
- 【分类号】R473.5
- 【被引频次】5
- 【下载频次】80