【摘要】 目的分析鼻窦低分化神经内分泌癌的CT、MRI表现,探讨其诊断要点。方法回顾性分析5例鼻窦低分化神经内分泌癌的CT、MRI特征及临床资料,所有患者均行MRI平扫及增强扫描,3例同时行CT扫描。结果 5例低分化神经内分泌癌,其中大细胞型1例,小细胞型4例。肿瘤位于蝶窦1例,筛窦3例,上颌窦1例。5例可见骨质破坏并侵犯邻近结构,骨破坏以膨胀性、吸收性为主,程度轻。累及翼腭窝1例,颞下窝2例,眼内直肌受累3例,颅底受累1例,鼻腔受累4例。2例直径>3cm,呈不规则分叶状,3例直径<3cm,呈椭圆形。CT、MRI表现为均匀密度或有线环状或葡萄状囊变密度或信号,1例有线环状钙化,但程度轻。T1WI为等信号,与周围脑组织信号相仿,T2WI呈等或稍高信号,明显低于脑脊液信号,增强扫描呈中度较明显强化,强化不均匀,但程度较轻。结论鼻窦低分化神经内分泌癌虽表现为恶性,但骨破坏程度轻,瘤体密度欠均匀,有线环状或葡萄状囊变密度或信号,T1WI呈等信号,T2WI呈等信号或稍高信号,明显低于正常脑脊液信号,增强扫描呈中度较明显强化。更多还原

【Abstract】 Objective The CT and MRI features of poorly differentiated neuroendocrine carcinoma(PNEC) in the paranasal sinus were studied for the purpose to improve the diagnosis of the disease.Methods Five cases of PNEC were retrospectively analyzed.All patients underwent plain and enhanced MRI scan,3 patients also underwent CT scanning.Results Five cases of PNEC include 1 case of large cell type,4 cases of small cell type.One case was located in sphenoid sinus,3 cases were in ethmoid sinus,1 case was in maxillary sinus.Five cases showed bone destructived with adjacent structures,showing bone expansion and absorbed,but to a less degree.1 cases were involved pterygopalatine fossa,2 cases were involved temporal fossa,3 cases were involved adducens oculi muscle,1 case were involved skull base,4 cases were involved nasal cavity.2 cases diameter were > 3cm,showing irregular lobulated,3 cases were <3cm,showing oval-shaped.CT,MRI performance: A more homogeneous density or signal,strip cystic density or signal was seen,but to a less degree;On MRI features,T1-weighted image showed equal signal,and the signal was similar to the surrounding brain tissue.T2-weighted image showed equal or slightly higher signal,but significantly lower than the CSF signal.After contrast injection,the tumors showed a more marked uniform enhancement.Conclusions Although the PNEC in the paranasal sinuses was malignant,showing a mild bone destruction.The density of tumor showed uniformity,T1-weighted image showed equal signal,T2-weighted image showed equal signals or slightly higher signal,significantly lower than the normal CSF signal;After contrast injection,they showed moderate ~ strengthening enhancement.更多还原