节点文献
盐酸纳洛酮在急性酒精中毒患者中的临床应用观察
Observation on clinical application of naloxone in acute alcoholism
【摘要】 目的研究盐酸纳洛酮在急性酒精中毒患者中的临床应用。方法将86例患者随机分成两组,即对照组和实验组,每组43例,对照组采用常规治疗方法,实验组在对照组的基础上采用盐酸纳洛酮治疗,比较两组患者治疗的有效率,同时观察患者的见效时间及症状消失时间。结果对照组有效率为88.37%,实验组有效率为100%,两组总有效率比较差异有统计学意义(P<0.05);对照组的见效时间为(40.49±18.22)min,实验组为(21.33±9.14)min;对照组症状消失时间为(80.72±30.82)min,实验组为(39.66±14.75)min,两组比较差异有统计学意义(P<0.05)。结论盐酸纳洛酮治疗急性酒精中毒取得了较好的临床效果,能够缩短起效时间,有效的加快症状消失,能够有效的保护大脑的功能,利于机体功能的恢复。
【Abstract】 Objective To study the clinical application of naloxone in acute alcoholism. Methods 86 patients were randomly divided into two groups,namely the control group with 43 cases and experimental groups of 43 cases.The observation group was taken with conventional treatment,and the experimental group was taken with naloxone treatment based on the control group.The efficient for the two groups were compared.The effective time and time for symptoms disappeared were observed. Results The efficiency rate in the control group was 88.37%,the experimental group was 100.00%.The differences of the total effective difference between the two groups were statistically significant(P<0.05).The effective time of the control group was(40.49±18.22) min.,the experimental group(21.33±9.14) min;time of symptom control group was(80.72 ± 30.82) min.the experimental group was(39.66±14.75)min.the differences were statistically significant(P<0.05). Conclusions Naloxone treatment of acute alcoholism achieved good clinical results,the onset time can be shortened and take the effective acceleration of symptoms,can effectively protect the brain function to help the recovery of body function.
【Key words】 Naloxone hydrochloride Acute alcoholism Clinical application;
- 【文献出处】 齐齐哈尔医学院学报 ,Journal of Qiqihar University of Medicine , 编辑部邮箱 ,2012年01期
- 【分类号】R595.6
- 【被引频次】2
- 【下载频次】53