【摘要】 目的分析肱踝脉搏波传导速度(baPWV)与多种临床因素之间的关系,探讨baPWV的影响因素。方法随机抽取2010年5月—2010年11月来我院健康管理中心体检的1 764例体检者,进行baPWV检测。按照所测baPWV值分成两组,<1 400 cm/s者为低baPWV组(n=1 144),≥1 400 cm/s者为高baPWV组(n=620)。以baPWV值为应变量,以年龄、体质指数(BMI)、收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、空腹血糖、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、心率为自变量,进行相关分析及逐步回归分析。结果 (1)高baPWV组除HDL-C水平低于低baPWV组外,其余各指标水平均高于低baPWV组,差异有统计学意义(P<0.05)。(2)单因素相关分析显示,年龄、SBP、DBP、MAP、空腹血糖、心率与baPWV呈正相关(P<0.05)。(3)多元线性回归分析显示,年龄、SBP、心率是baPWV的影响因素(P=0.00)。回归方程:baPWV=-255.97+8.024×年龄+7.681×SBP+5.877×心率。结论 baPWV与多种心血管疾病的影响因素有关,年龄、SBP和心率是其主要影响因素。更多还原

【Abstract】 Objective To study influencing factors of brachialankle pulse wave velocity and its relationship with the risk factors of cardiovscular disease.Methods Totally 1 764 healthy subjects who received health check-ups in our center from May 2010 to November 2010 were enrolled for baPWV measurement.Based on the results,these subjects were divided into low baPWV group(baPWV<1 400 cm/s)and hig baPWV group(baPWV>1 400 cm/s).With the baPWV value as the dependent variable and age,body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),mean artery pressure(MAP),fasting blood glucose(Glu),blood cholesterol(TC),blood glycerin(TG),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),and heart rate(HR) as the independent variables,the correlations between baPWV and the risk factors of cardiovascular diseases were analyzed.Results The age,BMI,SBP,DBP,MAP,Glu,TC,TG,and LDL-C were significantly higher in the high baPWV group than in the low baPWV group(P<0.05).Univariate analysis showed that the age,SBP,DBP,MAP,GLU and HR was significantly correlated with baPWV(P<0.05).Multivariate Logistic regression analysis showed that age,SBP and HR were positively correlated with baPWV(P=0.00).Conclusion baPWV can be a useful predictor of cardiovascular diseases.Age,SBP and HR are the main influential factors of baPWV.更多还原