【摘要】 用1 H NMR和13 C NMR研究了水溶性镧系位移试剂Sm-pdta对反式-4-羟基脯氨酸的手性识别.反式-4-羟基脯氨酸与Sm-pdta形成络合物后,其1 H NMR和13 C NMR图谱的化学位移有所变化,手性碳附近的某些原子所对应的吸收峰裂分为2组信号,分别对应反式-4-羟基脯氨酸的两种对映异构体.结果显示,对于反式-4-羟基脯胺酸,Sm-pdta是一个既方便又有效的手性位移试剂.更多还原

【Abstract】 1H and 13C NMR spectroscopy was carried out to investigate the chiral recognition of trans-4-hydroxyproline using water-soluble chiral lanthanide shift reagent Sm-pdta.When complexed with Sm-pdta,most signals in the 1H and 13C NMR spectra of trans-4-hydroxy-L-proline and trans-4-hydroxy-D-proline were shifted,leading to separation of the signals from the two enantiomers.The results showed that Sm-pdta is an effective reagent for chiral recognition of trans-4-hydroxyproline.更多还原