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心型脂肪酸结合蛋白与急性脑梗死

Heart-Type Fatty Acid-Binding Protein and Acut Cerebral Infraction

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【作者】 尚敏王萍

【Author】 SHANG Min,WANG Ping(Baotou Postgraduate Medical School,Baotou 014010 China)

【机构】 包头医学院研究生院

【摘要】 心型脂肪酸结合蛋白是一种可溶性细胞质蛋白,在脑细胞内有所表达。当病人患急性脑梗死时,早期心型脂肪酸结合蛋白水平明显升高,敏感性优于传统的生物学指标神经元特异性烯醇化酶(NSE)及S100B,浓度与脑梗死的面积和神经缺损功能相关联,有可能成为早期诊断脑梗死的新型生物学指标。

【Abstract】 Heart-type fatty acid-binding protein is a soluble cytoplasmic protein,and expressed in the brain cells.The levels of heart-type fatty acid-binding protein were significantly increased in serum in the early stage of cerebral infarction,While pati-ents were suffering from acute cerebral infarction.it is more sensitive than conventional neuro-biochemical markers,named neuron specific enolase(NSE) and S100B.The concentrations of serum were associated with the areas and injured neurological functions.So it is potential to be a new type of neuro-biochemical markers for the early diagnosis of cerebral infarction.

  • 【文献出处】 内蒙古医学杂志 ,Inner Mongolia Medical Journal , 编辑部邮箱 ,2012年08期
  • 【分类号】R743.3
  • 【被引频次】2
  • 【下载频次】70
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