【摘要】 目的探讨磁共振扩散成像表观扩散系数(ADC)评价良、恶性梗阻性黄疸的功能及鉴别良、恶性梗阻的价值。方法选择32例恶性梗阻性黄疸患者为恶性组,25例良性梗阻性黄疸患者为良性组,12例健康志愿者为对照组,进行磁共振扩散加权成像检查,计算对照组、不同病例组之间的ADC值,比较各组之间的差异。结果病例组组间ADC值比较,差异无统计学意义。不同病例组ADC值与对照组比较,差异有统计学意义(P<0.05)。结论肝脏ADC的测量可以评价梗阻性黄疸的肝脏功能,但不能鉴别梗阻的良、恶性。更多还原

【Abstract】 Objective To analyze the features of benign and malignant obstructive jaundice diffusion-weighted echo-planar magnetic resonance images,and to investigate the value of apparent diffusion coefficients(ADC) in liver function.Methods Thirty-two patients with malignant obstructive jaundice,twenty-five patients with benign obstructive jaundice and twelve normal volunteers(the control group) were studied by using diffusion-weighted imaging.ADC values were measured in malignant obstructive jaundice group,benign obstructive jaundice group and control group.Then one-way ANOVA test was used for statistical analysis.Results The ADC values in control group were significantly higher(P<0.05) than in malignant obstructive jaundice group and benign obstructive jaundice group.There was no significant difference between the apparent diffusion coefficients in malignant obstructive jaundice group and benign obstructive jaundice group.Conclusion ADC values can evaluate the liver function of obstructive jaundice but can not determine whether it is benign or malignant.更多还原