【摘要】 目的 :应用二维斑点追踪成像(Two-dimensional speckle tracking imaging,2DSTI)技术测量2型糖尿病(Type 2diabetes mellitus,T2DM)患者左室心肌旋转指标,探讨2DSTI技术评价T2DM患者左室心肌旋转运动的临床价值。方法 :采集43例T2DM患者(无微血管病变组20例,合并微血管病变组23例)和30例正常人的左室短轴二尖瓣水平、心尖水平切面二维高帧频声像图,测量内膜下(Prot-endo)、外膜下(Prot-epi)、切面整体(Prot)及跨壁角度梯度峰值(Prot-mur)。结果:①从正常对照组到糖尿病合并微血管病变组心尖水平Prot-endo、Prot-epi、Prot、二尖瓣水平Prot-epi递增(P<0.05),而心尖水平Prot-mur递减(P<0.05);②糖尿病合并微血管病变组的二尖瓣水平Prot-endo较正常对照组增高(P<0.05);③与正常对照组比较,糖尿病患者的二尖瓣水平Prot-mur减低、二尖瓣水平Prot增高(P<0.05)。结论:2DSTI技术能够准确测量T2DM患者左室短轴二尖瓣水平、心尖水平切面Prot-endo、Prot-epi、Prot及Prot-mur的变化,敏感评价T2DM患者心功能状态。更多还原

【Abstract】 Objective: To observe the rotation parameter of left ventricular short-axis views in the subendocardial and subepicardial myocardium layers by two-dimensional speckle tracking imaging(2DSTl),and to evaluate its performance in patients with type 2 diabetes mellitus(T2DM).Methods: Fourty-three patients with T2DM(20 patients without microangiopathy,23 patients with microangiopathy),and 30 cases of healthy volunteers as control were included in the study.High frame rate dynamic two-dimensional images were recorded at the left ventricular short-axis view,including basal and apical planes.The peak subendocardial rotation(Prot-endo),peak subepicardial rotation(Prot-epi),peak bulk rotation(Prot),and peak mural rotation(Prot-mur) were measured.Results: ①The apical Prot-endo,Prot-epi,Prot and the basal Prot-epi were higher and the apical Prot-mur was lower in control group than the T2DM group with microangiopathy(P<0.05).②The basal Prot-endo of T2DM patients with microangiopathy was significantly lower than that in control group.③When compared to the control group,the basal Prot-mur decreased while the basal Prot increased in the T2DM group(P<0.05).Conclusions: The 2DSTI can accurately evaluate the characteristics of left ventricular rotation parameter and sensitively evaluate the cardiac function in patients with T2DM.更多还原